Literature Review

Literature Review
EOSINOPHILIC ESOPHAGTIS

Peter R. McNally, DO, FACP, FACG
University of Colorado School of Medicine
Center for Human Simulation
Aurora, Colorado

VHJOE Editor:

John Deutsch, MD
St. Mary's Duluth Clinic

International Editor:

Manoop S. Bhutani, MD
MD Anderson Cancer Center
Houston, TX

Editorial Board:

William R. Brugge, MD
Massachusetts General Hospital

Peter R. McNally, DO
Denver, CO

Thomas J. Savides, MD
University of California,
San Diego

C. Mel Wilcox, MD
University of Alabama, Birmingham

In this edition of VHJOE, Literature in Review, we examine two articles that emphasize the emerging importance of Eosinophilic Esophagitis (EOE). These investigators demonstrated the EE is a disorder found across America, seen in both genders at all age groups and is often associated with atopic disorders.

Eosinophilic esophagitis: a prevalent disease in the United States that affects all age groups.

Kapel RC, Miller JK, Torres C, Aksoy S, et al.
Gastroenterology. 2008;134:1316-1321.

Introduction

Kapel, et al, combine to examine a national community based GI pathology referral of patients with GI disorders. This extensive database included over 400,00 patients from 34 states with GI disorders. The authors demonstrate that EOE is common, the disorder exhibits striking male predominance (3:1) and that presenting symptom of adults is dysphagia, while in children the presenting symptom is GERD.

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Atopic characteristics of adult patients with eosinophilic esophagitis.

Roy-Ghanta S, Larosa DF, Katzka DA.
Clinical Gastroenterology and Hepatology. 2008;6:531-535.

Introduction

Roy-Ghanta, et al, examine a cohort of patients (N=32) with EOE for allergic disorders. They are able to characterize the atopic diathesis of this patients and show that environmental and food allergies are common among adults with EOE.

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